The best known place called Epworth is the Town in the Isle of Axholme, Lincolnshire
Epworth is most famous as the Birthplace of John Wesley, founder of the Methodist Church.
This singular event has led to the name Epworth being used throughout the world for churches, hospitals, schools, halls and nearby roads, many of which are associated with the Methodist Church.
For example, the Epworth Press on Epworth Street London, UK, is the Methodist publishing house.
There are quite a few Places called Epworth in the USA:
And elsewhere